俄亥俄州立大學(Ohio State University)的研究表明給患有結(jié)腸腫瘤以及食管腫瘤的老鼠注入糙莓漿果之后，腫瘤有著明顯的縮小。同時，樹莓和黑莓的提取物可以有效緩解乳房癌、宮頸癌、結(jié)腸癌以及食道癌的發(fā)作。計算黑莓提取物對結(jié)腸癌以及食道癌的影響的臨床試驗已經(jīng)開始。
Mac Black源自北美，5年前被英國最大的漿果種植園發(fā)現(xiàn)并移植去英國，從那時候開始它就大面積繁殖并開始進入市場。作為新品種，并且價格便宜干凈衛(wèi)生，2英鎊就可以買到125g。
Mac Black開始特供特斯科(Tesco),買方詹姆斯·樊迪(James Waddy)說，“自從民眾開始意識到健康的重要性之后，對漿果的需求量開始日益增多。因此，從今年春天開始我們就大力培育這種果漿，而且今年有著20年來最溫暖的春天，因此連果汁都比以前的飽滿。我們堅信Mac Black將會成為漿果之王，有一天也會超過傳統(tǒng)的紅色品種的市場份額。”
推薦原文出處：
Seminars in Cancer Biology doi:10.1016/j.semcancer.2007.05.001
Cancer prevention with freeze-dried berries and berry components
Gary D. Stoner, Li-Shu Wang, Nancy Zikri , Tong Chen, Stephen S. Hecht, Chuanshu Huang, Christine Sardo, and John F. Lechner
Our laboratory is developing a food-based approach to the prevention of esophageal and colon cancer utilizing freeze-dried berries and berry extracts. Dietary freeze-dried berries were shown to inhibit chemically induced cancer of the rodent esophagus by 30–60% and of the colon by up to 80%. The berries are effective at both the initiation and promotion/progression stages of tumor development. Berries inhibit tumor initiation events by influencing carcinogen metabolism, resulting in reduced levels of carcinogen-induced DNA damage. They inhibit promotion/progression events by reducing the growth rate of pre-malignant cells, promoting apoptosis, reducing parameters of tissue inflammation and inhibiting angiogenesis. On a molecular level, berries modulate the expression of genes involved with proliferation, apoptosis, inflammation and angiogenesis. We have recently initiated clinical trials; results from a toxicity study indicated that freeze-dried black raspberries are well tolerated in humans when administered orally for 7 days at a dose of 45 g per day. Several Phase IIa clinical trials are underway in patients at high risk for esophagus and colon cancer; i.e., Barrett's esophagus, esophageal dysplasia and colonic polyps, to determine if berries will modulate various histological and molecular biomarkers of development of these diseases.
Keywords: Black raspberries; Colon; Esophagus; Cancer; Prevention
